High fidelity legacy-to-modern method transfer on the 6475 triple quadrupole LC/MS platform for large output production labs

2023/08/15   下载量: 2

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应用领域 电子/电气
检测样本 生活及清洁家电
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Large output production labs often resist changes in physical hardware or software revision despite improved performance or enhanced features due to the time consuming nature of re-verification, re-validation, or reconstruction of the analytical method. Often, the method needs to be “rebuilt”, using the former method as a template – possibly leading to transcription errors or unexpected performance differences.

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The new 6475 triple quadrupole LC/MS system with MassHunter 12 utilizes a unique metadata framework that assists in the direct transfer, import, and resolution of previously created methods. Methods are meant to be directly opened in the acquisition system, such that production labs with a large library of in-use methods require minimum effort for transfer into the new platform.


Here we present a demonstration and metadata framework to handle the direct method transfer from a “legacy” triple quadrupole LC/MS instrument to a

novel triple quadrupole LC/MS hardware and software platform with minimal adjustments and similar performance for accelerated incorporation into the production environment.


上一篇 采用液相色谱-四极杆串联飞行时间高分辨质谱分析锂电池中的碳酸酯有机溶剂组分
下一篇 使用 Agilent 8890/5977C GC/MSD 提高半挥发性有机化合物的分析灵敏度

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