NFKBIB抗原(重组蛋白)

参考价:¥3580
供货周期: 现货
品牌: MlBio/酶联生物
规格: 1mg
货号: ml-k013774
CAS号:
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NFKBIB抗原(重组蛋白)


中文名称: NFKBIB抗原(重组蛋白)


英文名称: NFKBIB Antigen (Recombinant Protein)


储 存:    冷冻(-20℃)


相关类别: 抗原


概 述

 

Fusion protein corresponding to C terminal 250 amino acids of human NFKBIB

 

技术规格

 

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Synonyms:

IKBB; TRIP9

Swissprot:

Q15653

Gene Accession:

BC015528

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.

 


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