NFKBID抗原(重组蛋白)

参考价:¥3580
供货周期: 现货
品牌: MlBio/酶联生物
规格: 1mg
货号: ml-k013775
CAS号:
上海酶联生物科技有限公司
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NFKBID抗原(重组蛋白)


中文名称: NFKBID抗原(重组蛋白)


英文名称: NFKBID Antigen (Recombinant Protein)


储 存:    冷冻(-20℃)


相关类别: 抗原


概 述

 

Fusion protein corresponding to a region derived from 1-221 amino acids of human NFKBID

 

技术规格

 

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

Synonyms:

TA-NFKBH, IkappaBNS

Swissprot:

Q8NI38

Gene Accession:

BC006273

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

 


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