OVA Conjugated Angiotensin II (AngII) XY95456CPSHu21_价格

产品详情

OVA Conjugated Angiotensin II (AngII)

血管紧张素Ⅱ(AngII)卵白蛋白偶联物

[ PROPERTIES ]

Antigen: AngII-OVA

Residues: Synthetic Peptide

Predicted isoelectric point: 6.7

Predicted Molecular Mass: 1046.2Da

Purity: >95%

Endotoxin Level: <1.0EU per 1μg (determined by the LAL method).

Formulation: Supplied as lyophilized form in PBS, pH7.4, containing5%trehalose, 0.01% sarcosyl.

Applications: SDS-PAGE; WB; ELISA; IP.

(May be suitable for use in other assays to be determined by the end user.)

[ RELEVANCE ]

Angiotensin is a peptide hormone that causes vasoconstriction and a subsequentincrease in blood pressure. It is part of the renin-angiotensin system, whichisamajor target for drugs that lower blood pressure. Angiotensin II actsasanendocrine, autocrine/paracrine, and intracrine hormone. Angiotensin II increasesblood pressure by stimulating the Gq protein in vascular smooth musclecells. Inaddition, angiotensin II acts at the Na/H exchanger in the proximal tubulesof thekidney to stimulate Na reabsorption and H excretion which is coupledtobicarbonate reabsorption. This ultimately results in an increase in bloodvolume,pressure, and pH. Hence, ACE inhibitors are major anti-hypertensive drugs.

[ USAGE ]

Reconstitute in sterile PBS, pH7.2-pH7.4.

[ STORAGE AND STABILITY ]

Storage: Avoid repeated freeze/thaw cycles.

Store at 2-8ºC for one month.

Aliquot and store at -80ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate of thetargetprotein. The loss rate was determined by accelerated thermal degradationtest,that is, incubate the protein at 37ºC for 48h, and no obvious degradationandprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.)The loss of this proteinislessthan 5% within the expiration date under appropriate storage condition.

[ SEQUENCES ]

The synthetic peptide’s sequence is listed below.

DRVYIHPF

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供货周期：	现货
品牌：	信裕生物
规格：	10ug/50ug/200ug/1mg
货号：	XY95456CPSHu21
CAS号：