| 供货周期： | 现货 |
| 品牌： | Sigma-Aldrich |
| 规格： | AR级别，99% |
| 货号： | B128570 |
| CAS号： |
Product Name: Butyrylcholinesterase from equine serum
| 别名: | BChE |
| CAS号: | 9001-08-5 |
| EINECS编号: | 232-579-2 |
| MDL号: | MFCD00081455 |
| 介绍: | Butyrl Cholinesterase catalyzes the hydrolysis of a number of choline esters according to the following reaction:Acylcholine + H2O → choline + acid It is a tetrameric glycoprotein with four subunits of equal size, each having a molecular weight of 110 kDa. Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine. Unlike acetyl cholinesterase, it does not hydrolyze D-≥-methyl acetylcholine. It is inhibited by 10-5 M physostigmine, numerous organophosphate esters, the carbamate derivates and quaternary ammonium salts. |
| 用途: | Selective inhibition of BChE activity can be used in the detection of organophosphates.Its use in the treatment of organophosphate toxicity has been explored. It has been reported that the level of BChE in human blood correlates to the degree of protection against potentially toxic nerve agents.Cholinesterases have also been investigated for their role in Alzheimer’s disease. |
| 贮存: | 储存温度 2-8°C |
| 生化和生理学机理: | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substrate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. |
相关产品
GelstainRedTM 核酸染料, 10,000× in water
Super GelBlueTM 核酸染料, 10,000× in water
彩色预染蛋白Marker（10-180 kDa，三色）
彩色预染蛋白Marker（10-250kDa, 双色）
琼脂糖 A2015
Super ECL Plus（超敏化学发光检测试剂盒） S6009M
PAGE 彩色快速凝胶制备试剂盒（10%）
Minerva Super Fusion Cloning Kit（无缝克隆试剂盒）
Cell Counting Kit-8（CCK-8）细胞增殖检测试剂盒
FITC-Annexin V/PI 细胞凋亡试剂盒
1,5-AG(1,5-Anhydroglucitol) ELISA Kit XY9U2590
Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) XY95200RPHu01
Recombinant Spindlin 1 (SPIN1) XY94760RPHu
OVA Conjugated Leucine (Leu) XY95654CPSGe
Recombinant Peroxiredoxin 5 (PRDX5) XY93776RPMu02
关注
拨打电话
留言咨询
