Recombinant Human FGF-23_价格_上海远慕生物科技有限公司

产品详情

The FGF family plays a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant Human FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-23

AA Sequence: MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50 for this effect is 2.0-5.0 μg/ml, in the presence of murine Klotho and heparin.
Recombinant Human FGF-23 Biological Activity Graph

Calculated Molecular Weight: 25.5 kDa

Accession Number: Q9GZV9

Gene ID: 8074

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Cross Reactivity Cited in References:
Mouse, Rat

Recombinant Human FGF-23信息由上海远慕生物科技有限公司为您提供，如您想了解更多关于Recombinant Human FGF-23报价、型号、参数等信息，欢迎来电或留言咨询。除供应Recombinant Human FGF-23外，上海远慕生物科技有限公司还可为您提供其他等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	两周
品牌：	派普泰克
规格：	100ug
货号：	100-52-100ug
CAS号：