Animal-Free Recombinant Human BMP-4 (E.coli derived)

参考价:面议
供货周期: 两周
品牌: 派普泰克
规格: 100ug
货号: AF-120-05ET-100ug
CAS号:
上海远慕生物科技有限公司
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Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor.  The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa.

Manufactured using all Animal-Free reagents.


Source: E.coli


Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4


AA Sequence (monomer): KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR


Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.


Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.

Animal-Free Recombinant Human BMP-4 (E.coli derived) Biological Activity Graph


Calculated Molecular Weight: 23.9 kDa


Accession Number: P12644


Gene ID: 652


Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)


Note:

1mg will be provided as 2x500μg.


crossreactivity:

Human, Mouse, Rat, Salamander


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