岛素样生长因子结合蛋白样1抗体

参考价:¥1
供货周期: 现货
品牌: GenWay
规格: 0.1ml/100μg 0.2ml/200μg
货号: FSSW0014
CAS号:
上海抚生实业有限公司
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公司胰岛素样生长因子结合蛋白样1抗体具有高纯度、高效价、高特异性的特点,仅用于科学研究,不可用于临床诊断及药物治疗,可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-IGFBPL1

中文名称  胰岛素样生长因子结合蛋白样1抗体

别    名  bA113O24.1; IGFBP-related protein 10; IGFBP-RP4; IGFBPRP4; insulin-like growth factor binding protein related protein 4; insulin-like growth factor-binding protein-like 1; IBPL1_HUMAN; insulin-like growth factor-binding-related protein 4.

浓    度  1mg/1ml

规 格  0.2ml/200μg  
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胰岛素样生长因子结合蛋白样1抗体抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

产品类型  一抗    

研究领域  细胞生物 免疫学 信号转导 生长因子和激素  

蛋白分子量  predicted molecular weight: 26kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IGFBPL1

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

(石蜡切片需做抗原修复)

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is found at lower levels in the prostate, bladder and lung.

Function : IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.

Subcellular Location : Secreted.

Tissue Specificity : Expressed at the highest level in both brain and testis, with 胰岛素样生长因子结合蛋白样1抗体lower levels in the prostate, bladder and lung.

Similarity : Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Contains 1 IGFBP N-terminal domain.

Contains 1 Kazal-like domain.

Database links : UniProtKB/Swiss-Prot: Q8WX77.1

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