原钙粘蛋白γB5抗体_价格_上海抚生实业有限公司

产品详情

公司原钙粘蛋白γB5抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称 Anti-PCDHGB5

中文名称 原钙粘蛋白γB5抗体

别名 PCDH gamma B5; PCDHGB 5; Protocadherin gamma B5; Protocadherin gamma subfamily B 5; PCDGH_HUMAN.

浓度 1mg/1ml

规格 0.2ml/200μg
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原钙粘蛋白γB5抗体抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域肿瘤细胞生物神经生物学信号转导细胞粘附分子细胞表面分子

蛋白分子量 predicted molecular weight: 97kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human PCDHGB5

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Function : Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the 原钙粘蛋白γB5抗体rain.

Subcellular Location : Cell membrane; Single-pass type I membrane protein (By similarity).

Similarity : Contains 6 cadherin domains.

Database links : UniProtKB/Swiss-Prot: Q9Y5G0.1

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供货周期：	现货
品牌：	GenWay
规格：	0.1ml/100μg 0.2ml/200μg
货号：	FSSW0852
CAS号：