嘌呤核苷磷酸化酶抗体

公司嘌呤核苷磷酸化酶抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-PNP/Nucleoside phosphorylase 

中文名称  嘌呤核苷磷酸化酶抗体 

别    名  Inosine phosphorylase; MGC117396; MGC125915; MGC125916; NP; Np1; Nucleoside phosphorylase; PNP; Pnp1; PNPH_HUMAN; PRO1837; PUNP; Purine nucleoside orthophosphate ribosyltransferase; Purine nucleoside phosphorylase; FLJ94043; FLJ97288. 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg
嘌呤核苷磷酸化酶抗体 的相关产品:

Rabbit anti-Monkey IgM whole serum  兔抗猴IgM抗血清 1ml

Rabbit Anti-Monkey IgM/AP  碱性磷酸酶（AP）标记的兔抗猴IgM 0.1ml

Rabbit Anti-Monkey IgM/Bio  生物素标记的兔抗猴IgM 0.3ml

Rabbit Anti-Monkey IgM/Cy3  Cy3标记的兔抗猴IgM 0.1ml 

嘌呤核苷磷酸化酶抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

产品类型  一抗    

研究领域  肿瘤 细胞生物 神经生物学 淋巴细胞 t-淋巴细胞  

蛋白分子量  predicted molecular weight: 32kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PNP/Nucleoside phosphorylase 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Purine nucleoside phosphorylase (PNP), also designated inosine phosphorylase, forms a homotrimer. It belongs to the PNP/MTAP phosphorylase family of proteins. Human PNP catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine, and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Children with PNP deficiency are highly prone to infections, autoimmune disorders, neurological impairment, and cancer.

Function : Defects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) [MIM:613179]. It leads to a severe T-cell immunodeficiency with neurologic disorder in children.

Subunit : Homotrimer. 

Subcellular Location : Cytoplasm, cytoskeleton (By similarity).Cytoplasm 

Tissue Specificity : Expressed in red blood cells; overexpressed inred blood cells (cytoplasm) of patients with hereditarynon-spherocytic hemolytic anemia of unknown etiology. 

DISEASE : Defects in PNP are the cause of purine nucleosidephosphorylase d嘌呤核苷磷酸化酶抗体eficiency (PNPD) [MIM:613179]. It leads to a severeT-cell immunodeficiency with neurologic disorder in children. 

Similarity : Belongs to the PNP/MTAP phosphorylase family.

Database links : UniProtKB/Swiss-Prot: P00491.2

公司提供嘌呤核苷磷酸化酶抗体价格绝对优势，欢迎新老客户来电垂询我公司优质抗体嘌呤核苷磷酸化酶抗体说明书及报价等。