供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.1ml/100μg 0.2ml/200μg |
货号: | FSSW0966 |
CAS号: |
以下为您提供的是磷脂酸磷酸酶2结构域3抗体的说明书,了解更多关于磷脂酸磷酸酶2结构域3抗体的英文名称,磷脂酸磷酸酶2结构域3抗体别名,磷脂酸磷酸酶2结构域3抗体规格,请看以下详细介绍.
英文名称 Anti-PPAPDC3
中文名称 磷脂酸磷酸酶2结构域3抗体
别 名 C9orf67; Phosphatidic acid phosphatase type 2 domain-containing protein 3; PPAC3_HUMAN; Ppapdc3; Probable lipid phosphate phosphatase PPAPDC3.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Rabbit
磷脂酸磷酸酶2结构域3抗体的多样性:
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
因为抗体具有与抗原决定簇相对应的结合部位(抗原结合簇),所以抗体与抗原的结合具有特异性。另一方面,抗体本身是一种蛋白质,具有本身的氨基酸组成、排列和立体结构,对异种动物来说,它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性,它们表现出不同的血清学类型。
磷脂酸磷酸酶2结构域3抗体的相关产品:
Rabbit Anti-human IgG F(ab')2/Alexa Fluor 555 Alexa Fluor 555标记的兔抗人IgG F(ab')2 0.1ml
Rabbit Anti-human IgG F(ab')2/Alexa Fluor 647 Alexa Fluor 647标记的兔抗人IgG F(ab')2 0.1ml
Rabbit Anti-human IgG F(ab')2/AP 碱性磷酸酶(AP)标记的兔抗人IgG F(ab')2 0.1ml
产品类型 一抗
研究领域 细胞生物 免疫学 干细胞 细胞周期蛋白 细胞分化
蛋白分子量 predicted molecular weight: 30kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PPAPDC3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity.PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
Function : Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity.
Subunit : Homo and heterooligomer. Interacts with MTOR; controls MTOR-dependent IGF2 expression during myoblast differentiation.
Subcellular Location : Nucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein. Note=Both the N-and C-terminal are 磷脂酸磷酸酶2结构域3抗体exposed to the cytoplasm/nucleoplasm.
Similarity : Belongs to the PA-phosphatase related phosphoesterase family.
Database links : UniProtKB/Swiss-Prot: Q8NBV4.1
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