原钙粘附蛋白20抗体_价格_上海抚生实业有限公司

产品详情

公司原钙粘附蛋白20抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称 Anti-PCDH20

中文名称 原钙粘附蛋白20抗体

别名 PCD20_HUMAN; PCDH 13; PCDH 20; PCDH13; PCDH20; Protocadherin 13; Protocadherin 20; Protocadherin-13; Protocadherin-20; Protocadherin13; Protocadherin20.

浓度 1mg/1ml

规格 0.2ml/200μg
原钙粘附蛋白20抗体的相关产品:

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原钙粘附蛋白20抗体抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Horse, Rabbit

产品类型一抗

研究领域神经生物学信号转导细胞粘附分子细胞骨架细胞外基质细胞膜蛋白

蛋白分子量 predicted molecular weight: 98kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human PCDH20

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. Protocadherin-20 (PCDH20), also known as protocadherin-13, is a 924 amino acid protein containing 6 cadherin domains and potentially functioning as a calcium-dependent cell-adhesion protein. In non-small cell lung cancer cell lines, a homozygous loss of PCDH20 was identified through either deletion of one allele and methylation of the other or methylation of both alleles. Hypermethylation of PCDH20 is associated with worse prognosis and clinical outcome, suggesting that PCDH20 may function as a tumor suppressor.

Function : Potential calcium-dependent cell-adhesion protein.

Subcellular Location : Cell membrane.

原钙粘附蛋白20抗体Similarity : Contains 6 cadherin domains.

Database links : UniProtKB/Swiss-Prot: Q8N6Y1.1

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供货周期：	现货
品牌：	GenWay
规格：	0.1ml/100μg 0.2ml/200μg
货号：	FSSW0981
CAS号：