| 供货周期： | 现货 |
| 品牌： | GenWay |
| 规格： | 0.1ml/100μg 0.2ml/200μg |
| 货号： | FSSW0985 |
| CAS号： |
公司原钙粘附蛋白α4抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。
英文名称 Anti-PCDHA4
中文名称 原钙粘附蛋白α4抗体
别 名 CNR1; CNRN1; CRNR1; Ortholog of mouse CNR1; PCDA4_HUMAN; PCDH alpha 4; PCDH ALPHA4; PCDH-alpha-4; PCDHA 4; PCDHA4; Protocadherin alpha 4; Protocadherin alpha-4.
浓 度 1mg/1ml
规 格 0.2ml/200μg
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原钙粘附蛋白α4抗体抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep
产品类型 一抗
研究领域 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白
蛋白分子量 predicted molecular weight: 99kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA4
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Members of the cadherin-related neuronal receptor (CNR) family, including PCDHA4 (also known as CNR1) and PCDHA6 (also known as CNR2), comprise a novel subfamily within the cadherin superfamily of adhesion molecules. The cadherin-related neuronal receptor proteins form a complex with Fyn, a protein tyrosine kinase that is involved in building brain networks and determining patterns of behavior. Cadherin-related neuronal receptor 1 and 2 were discovered during a search for receptor molecules to the Fyn signaling pathway in the mammalian brain. Members of the cadherin superfamily are Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The PCDHA4 and PCDHA6 extracellular domains contain six cadherin repeats that mediate Ca++-dependent cell adhesion, while the cytoplasmic domains are not homologous with other cadherins.
Function : Potential calcium-dependent cell-adhesion protein. May be involved 原钙粘附蛋白α4抗体in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Location : Cell membrane.
Similarity : Contains 6 cadherin domains.
Database links : UniProtKB/Swiss-Prot: Q9UN74.1
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