ADP核糖基化因子相关蛋白1

2015-01-27 09:12  下载量:0

资料摘要

资料下载

ADP核糖基化因子相关蛋白1 Background: The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis. Also known as: ADP ribosylation factor related protein 1; ARF related protein 1; ARF related protein; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein; ARFRP_HUMAN.ADP核糖基化因子相关蛋白1

资料下载

文献贡献者

资料中心 更多

相关产品

当前位置: 仪器信息网 沪震生物 资料 ADP核糖基化因子相关蛋白1

关注

拨打电话

留言咨询