BTRC2蛋白抗体

2015-01-29 10:00  下载量:0

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BTRC2蛋白抗体 Background: Beta TRCP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. Also known as: beta Transducin Repeat Containing Protein 2; BTRC2; BTRCP2; F-box and WD-40 Domain Protein 1B; F-box Protein FBW1B; FBW1B; FBXW1B; FBW1B_HUMAN.BTRC2蛋白抗体

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