供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-6251R |
CAS号: |
英文名称 ARK5
中文名称 AMPK的相关蛋白激酶5抗体
别 名 AMPK related protein kinase 5; NUAK family SNF1 like kinase; NUAK1; Probable serine/threonine protein kinase KIAA0537.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 免疫学 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 AMPK的相关蛋白激酶5抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARK5
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
AMPK的相关蛋白激酶5抗体产品介绍 background:
ARK5, a novel AMPK family member, is the tumor cell survival factor activated by Akt and acts as an ATM kinase under the conditions of nutrient starvation. It plays a key role in tumor malignancy downstream of Akt. Its overexpression is associated with tumor invasion and metastasis.
Function:
Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
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