供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-6336R |
CAS号: |
英文名称 APOB48R
中文名称 载脂蛋白B受体抗体
别 名 apo b-100; APOB; apoB-48R; apoB-100R; apoB100R; Apolipoprotein B-100 receptor; Apolipoprotein B100 receptor; Apolipoprotein B48 receptor.
说 明 书 0.2ml
研究领域 心血管 细胞生物 免疫学 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Rabbit,
产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 载脂蛋白B受体抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 115kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APOB48R
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
载脂蛋白B受体抗体产品介绍 background:
APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. It may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells.
Function:
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.
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