凋亡诱导蛋白D抗体

英文名称    APPD    

中文名称    凋亡诱导蛋白D抗体    

别    名    PKHF1_HUMAN; Apoptosis inducing protein D; LAPF; Lysosome associated apoptosis inducing protein containing PH and FYVE domains; MGC4090; PH and FYVE domain containing protein 1; PH domain containing family F member 1; Phafin 1; Pleckstrin homology domain containing family F (with FYVE domain) member 1; Pleckstrin homology domain containing family F member 1; Pleckstrin homology domain containing family F with FYVE domain member 1; PLEKHF1; ZFYVE15; Zinc finger FYVE domain containing protein 15.    

说 明 书    0.2ml      

研究领域    细胞生物  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500凋亡诱导蛋白D抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    31kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human APPD/LAPF (75-124aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

凋亡诱导蛋白D抗体产品介绍    background:

APPD is a lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF). It is a representative of a novel family of PH and FYVE domain-containing proteins and induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway. Cellular localization: Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis.

Function:
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.    

凋亡诱导蛋白D抗体公司更多热销抗体产品如下：

hz-1094 sTLR2 ELISA Kit  大鼠可溶性Toll样受体2

hz-1094 sLR(Mouse Leptin Soluble Receptor) ELISA Kit  小鼠可溶性瘦素受体

hz-1095 VEGF-B(Human Vascular Endothelial cell Growth Factor B) ELISA KIT  人血管内皮细胞生长因子B

hz-1095 PGF2 Alpha ELISA Kit  大鼠前列腺素F2α

hz-1095 Beta-EPR(Mouse Beta-Endorphin receptor) ELISA Kit  小鼠β内啡肽受体

hz-1096 VEGF(Human Vascular Endothelial cell Growth Factor) ELISA KIT  人血管内皮细胞生长因子

hz-1096 LTE4 ELISA Kit  大鼠白三烯E4

hz-1096 HL(Mouse hepatic lipase) ELISA Kit  小鼠肝脂酶

hz-1097 UK ELISA Kit  大鼠尿激酶

hz-1097 VCAM-1/CD106(Human Vascuolar cell adhesion molecule 1) ELISA kit  人血管内皮细胞粘附分子1

hz-1097 HBcAb(Mouse hepatitis B virus core antibody) ELISA Kit  小鼠乙型肝炎核心抗体

hz-1098 HBeAb(Mouse hepatitis B virus e antibody) ELISA Kit  小鼠乙型肝炎e抗体

hz-1098 sTRAIL(Human soluble tumor necrosis factor-related apoptosis inducing ligand) ELISA KIT  人可溶性肿瘤坏死因子相关凋亡诱导配体

hz-1098 F XII ELISA Kit  大鼠凝血因子Ⅻ

hz-1099 F X III ELISA Kit  大鼠凝血因子ⅩⅢ

hz-1099 TRAIL-R4(Human tumor necrosis factor-related apoptosis-inducing ligand 4) ELISA Kit  人肿瘤坏死因子相关凋亡诱导配体4

hz-1099 HBeAg(Mouse hepatitis B virus e antigen) ELISA Kit  小鼠乙型肝炎e抗原

hz-1100 TRAIL-R3(Human tumor necrosis factor-related apoptosis-inducing ligand 3) ELISA Kit  人肿瘤坏死因子相关凋亡诱导配体3

hz-1100 F III ELISA Kit  大鼠凝血因子Ⅲ

hz-1100 HBsAb(Mouse hepatitis B virus surface antibody) ELISA Kit  小鼠乙型肝炎表面抗体

hz-1101 DAO(Mouse diamine oxidase) ELISA Kit  小鼠二胺氧化酶

hz-1101 Apo-H ELISA Kit   大鼠载脂蛋白H

hz-1101 TRAIL-R1(Human tumor necrosis factor-related apoptosis-inducing ligand 1) ELISA Kit  人肿瘤坏死因子相关凋亡诱导配体1

hz-1102 TNF- Beta(Human Tumor necrosis factor Beta) ELISA KIT  人肿瘤坏死因子β