铁蛋白Fe65样蛋白2抗体

英文名称    APBB3    

中文名称    铁蛋白Fe65样蛋白2抗体    

别    名    FE65L2; Amyloid beta A4 precursor protein binding family B member 3; Amyloid beta A4 precursor protein-binding family B member 3; amyloid beta precursor protein binding family B member 3; amyloid precursor interacting protein; Apbb3; APBB3_HUMAN; Fe65 like protein 2; FE65L2; Protein Fe65-like 2; SRA.    

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  信号转导  Alzheimer's      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 铁蛋白Fe65样蛋白2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    52kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human APBB3/FE65L2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 铁蛋白Fe65样蛋白2抗体产品介绍    background:

Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Function:
May modulate the internalization of beta-amyloid precursor protein.    

铁蛋白Fe65样蛋白2抗体公司更多热销抗体产品如下：

hz-1465P GRB2/ASH peptide  生长因子受体结合蛋白2抗原

hz-1351P GZMB/CCPI(Granzyme B)  颗粒酶B抗原

hz-1806P UTS2R/GPR14(Urotensin II receptor：G Protein Coupled Receptor 14)  G蛋白偶联受体14抗原

hz-1380P GPR30(G Protein Coupled Receptor 30)  G蛋白偶联受体30抗原

hz-1464P GnRHR peptide  促性腺激素释放激素受体抗原

hz-2501P KiSS-1R/GPR54/GPCR54(KiSS-1 receptor/G-Protein Coupled Receptor 54)  G蛋白偶联受体54抗原

hz-1209P GRK2/BARK1 (G-protein coupled receptor kinase 2)  G蛋白偶合受体激酶2抗原

hz-1161P GRM2/GLUR2 (Glutamate Receptor Metabotropic 2)  促代谢型谷氨酸受体2抗原

hz-0863P GRO Alpha/GRO/MGSA/CXCL1 protein (growthregulated oncogene Alpha)  生长调节致癌基因α/黑素瘤生长刺激因子α 抗原

hz-1219P GRP78(glucose regulated protein 78)  葡萄糖调节蛋白78抗原（热休克蛋白70蛋白5）

hz-2091P GSK-3 Alpha (Glycogen Synthase Kinase-3 alpha)  葡萄糖合成激酶-3α抗原(多肽抗原)

hz-2066P phospho-GSK-3 Beta(pSer9)  磷酸化葡萄糖合成激酶-3β抗原

hz-2073P phospho-GSK3 Alpha/ Beta(alpha + beta)(phospho Tyr279 + Tyr216)  磷酸化葡萄糖合成激酶3α/β抗原

hz-0837P GSR/GRase(glutathione reductase)  谷胱甘肽还原酶抗原

hz-1430P A/H1N1-M2 Human(Avian influenza Matrix Protein-2 Human)  A型人流感病毒H1N1-M2蛋白多肽

hz-0422P A/H1N1-M2 Swine(Avian influenza Matrix Protein-2 Swine)  A型猪流感病毒H1N1-M2蛋白

hz-2001P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2002P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2560P H2AX peptide  组蛋白H2AX多肽抗原

hz-2003P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2004P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-1235P Haase(hyaluronidase)  透明质酸酶/玻璃酸酶抗原

hz-0843P HA tag  HA tag标签多肽

hz-0966P HA tag(map)  HA tag标签（分支多肽）