供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-9567R |
CAS号: |
英文名称 ANT1+ANT2+ANT3+ANT4
中文名称 腺嘌呤核苷酸转运蛋白1、2、3、4抗体
别 名 ATP carrier protein 1; ADP ATP carrier protein heart/skeletal muscle isoform T1; ADP/ATP translocase 1; ADT1_HUMAN; ANT 1; ANT; ANT1; ATP carrier protein 2; ADP ATP carrier protein heart/skeletal muscle isoform T2; ADP/ATP translocase 2; ADT2_HUMAN; ANT 2; ANT; ATP carrier protein 3; ADP ATP carrier protein heart/skeletal muscle isoform T3; ADP/ATP translocase 3; ADT3_HUMAN; ANT3; ATP carrier protein 4; ADP ATP carrier protein heart/skeletal muscle isoform T4; ADP/ATP translocase 4; ADT4_HUMAN; ANT 4;ANT4.
说 明 书 0.2ml
研究领域 心血管 细胞生物 神经生物学 信号转导 转录调节因子 G蛋白偶联受体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 腺嘌呤核苷酸转运蛋白1、2、3、4抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANT1/2/3/4
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
腺嘌呤核苷酸转运蛋白1、2、3、4抗体产品介绍 background:
Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
Function:
Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
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