供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-1011R |
CAS号: |
英文名称 CXCR4
中文名称 细胞表面趋化因子受体4抗体
别 名 C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; CD184 antigen; CXCR4_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 免疫学 细胞膜受体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 细胞表面趋化因子受体4抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from the middle of human CD184 (211-254aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
细胞表面趋化因子受体4抗体产品介绍 background:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Monomer. Can form dimers.
Function:
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.
细胞表面趋化因子受体4抗体
hz-7710R CENPP 着丝粒蛋白P抗体
hz-7711R PCNT/Pericentrin 中心粒周蛋白抗体
hz-7712R Importin4/RanBP4 核蛋白4抗体(Ran结合蛋白4)
hz-7713R MIS12 染色体及有丝分裂蛋白MIS12抗体
hz-7714R CDCA1/Nuf2 细胞分裂周期相关蛋白1抗体
hz-7715R Importin 9/RanBP9 核蛋白9抗体(Ran结合蛋白M)
hz-7716R SPC25 纺锤体极点构成蛋白25抗体
hz-7717R CDCA5/Sororin 细胞分裂周期相关蛋白5抗体
hz-7718R CAPD2/CNAP1 染色体相关蛋白2抗体
hz-7719R KRG2/DDX11 角质细胞生长因子调节蛋白2抗体
hz-7720R DSCC1 DSCC1蛋白抗体
hz-5285R phospho-CARM1(Ser228) 磷酸化蛋白精氨酸N甲基4抗体
hz-5575R phospho-PRKAA2(Ser173) 腺苷单磷酸活化蛋白激酶α2抗体
hz-7721R CAPG2/NCAPG2 染色体相关蛋白2抗体
hz-7722R APRIN/PDS5B 雄激素诱导增殖抑制蛋白抗体
hz-7723R REC8 减数分裂重组蛋白家族REC8抗体
hz-7724R SA1/Nuclear protein stromal antigen 1 粘结蛋白SA1抗体
hz-7725R SA2 粘结蛋白SA2抗体
hz-7726R phospho-REC8(Ser251) 磷酸化减数分裂重组蛋白家族REC8抗体
hz-7727R SMC2 染色体结构维持蛋白2抗体
hz-7728R SMC4 染色体结构维持蛋白4抗体
hz-7729R SMC5 染色体结构维持蛋白5抗体
hz-7730R SMC6 染色体结构维持蛋白6抗体
hz-7731R TRIP1/PSMC5 甲状腺受体相互作用蛋白1抗体
hz-7732R Separase 纺锤体级以外蛋白样1抗体
hz-7733R WAPL EBV核蛋白2抗体
hz-7734R CAPD3/hCAP-D3 浓缩素2复合亚基D3抗体
hz-7735R AMSH 信号转导衔接结合蛋白抗体
hz-7736R ASB3 锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族3抗体
hz-7737R EIF2C1/Ago1 真核翻译起始因子2C1抗体
hz-7738R Anillin 胞环蛋白肌动蛋白结合蛋白抗体
hz-7739R BIN3 细胞骨架衔接蛋白BIN3抗体
相关产品
关注
拨打电话
留言咨询