癌胚抗原抗体

英文名称    CEA    

中文名称    癌胚抗原抗体    

别    名    Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CD66e; CD66e antigen; CEA; CEA; CEACAM5; CEAM5_HUMAN; DKFZp781M2392; Meconium antigen 100; OTTHUMP00000199032; OTTHUMP00000199033; OTTHUMP00000199034.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学  干细胞  细胞类型标志物  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 癌胚抗原抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    150-200kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CEA C-terminus    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

癌胚抗原抗体产品介绍    background:

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Function:
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.    

癌胚抗原抗体

hz-7909R phospho-CK II beta(Ser209)  磷酸化丝氨酸/苏氨酸蛋白激酶II β(casein kinase IIβ)抗体

hz-7910R DUSP26/MKP8  双特异性蛋白磷酸酶26抗体（丝裂原活化蛋白激酶磷酸酶8）

hz-7911R phospho-FER/TYK3(Tyr402)  磷酸化酪氨酸蛋白激酶3抗体

hz-7912R GAK protein  细胞周期蛋白G相关激酶抗体

hz-7913R phospho-LATS1+LATS2 (Thr1079 +Thr1041)  磷酸化肿瘤抑制基因LATS1/LATS2抗体

hz-7914R MOBKL2B  Mob1同源蛋白MOBKL2B抗体

hz-7915R MOBKL2C  Mob1同源蛋白MOBKL2C抗体

hz-7916R N acetylglucosamine kinase  N-乙酰氨基葡萄糖激酶抗体

hz-7917R NUCKS1  核酪蛋白激酶和细胞周期蛋白依赖性激酶底物1抗体

hz-7918R PLK5  丝氨酸/苏氨酸蛋白激酶5抗体

hz-7919R phospho-MST1R(Tyr1353)   磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-7920R MAPK13/SAPK4/p38delta  丝裂原活化蛋白激酶13抗体

hz-7921R Robo2  轴突导向受体蛋白2抗体

hz-7922R SKAR  DNA聚合酶δ相互作用蛋白3抗体

hz-7923R SRPK2  丝氨酸/苏氨酸蛋白激酶SRPK2抗体

hz-7924R TBRG4  转化生长因子β调节蛋白4抗体

hz-7925R TLK2  丝氨酸/苏氨酸激酶TLK2抗体

hz-7926R ANKRD28  锚蛋白重复域28抗体

hz-7927R SIPA1L2  信号诱导增殖相关蛋白1样蛋白2抗体

hz-7928R DUSP7  双特异性蛋白磷酸酶7抗体

hz-7929R PPM1B  蛋白质磷酸酶1B抗体（PP2Cβ）

hz-7930R PPM1G  蛋白质磷酸酶1G抗体（PP2Cγ）

hz-7931R PPP2R1A  蛋白质磷酸酶2调节亚基1A抗体

hz-7932R PPP2R1B  蛋白质磷酸酶2调节亚基1B抗体

hz-7933R PPP2R3A  蛋白质磷酸酶2调节亚基3A抗体

hz-7934R SHOC2/Sur8  富含亮氨酸重复蛋白SHOC2抗体

hz-7935R RAMP/CDT2  维甲酸调节核基质相关蛋白

hz-7936R MTMR8  肌管素相关蛋白8抗体

hz-7937R NIFK  KI67相互作用蛋白抗体

hz-7938R phospho-NIFK/MKI67IP(Thr234)  磷酸化KI67相互作用蛋白抗体

hz-7939R TACC1  乳腺癌、胃癌抗原GA55抗体