CD10抗体

英文名称    CD10    

中文名称    CD10抗体    

别    名    Atriopeptidase; CALLA; CD 10; CD10; Common acute lymphocytic leukemia antigen; DKFZp686O16152; EC 3.4.24.11; Enkephalinase; EPN; gp100; Membrane metallo endopeptidase; Membrane metalloendopeptidase; Membrane metalloendopeptidase neutral endopeptidase enkephalinase; Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10; Membrane metalloendopeptidase variant 1; Membrane metalloendopeptidase variant 2; MGC126681; MGC126707; MME; NEP; Neprilysin; Neutral endopeptidase 24.11; Neutral endopeptidase; NEP_HUMAN; Neprilysin; Skin fibroblast elastase; SFE.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500CD10抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    82kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CD10    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

CD10抗体产品介绍    background:

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Function:
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.    

CD10抗体

hz-9109R MAP4K6/MINK1  丝裂原活化蛋白激酶MAP4K6抗体

hz-9110R ATAD2  三磷酸腺苷酶家族蛋白2抗体

hz-9112R ASMTL  ASMTL蛋白抗体

hz-9113R GPCR TAS1R3  G蛋白偶联受体TAS1R3抗体

hz-9114R BAGE2  肿瘤/睾丸抗原2.2抗体

hz-9115R BAGE3  肿瘤/睾丸抗原2.3抗体

hz-9116R BAGE4  肿瘤/睾丸抗原2.4抗体

hz-9118R KMT1C/G9a  组蛋白H3赖氨酸9甲基化1C抗体

hz-9119R COPS8  信号转导蛋白亚基8抗体

hz-9120R COPS6  信号转导蛋白亚基6抗体

hz-9121R FBXO21  F-box蛋白21抗体

hz-9122R FBXO38  F-box蛋白38抗体

hz-9123R COPS4  信号转导蛋白亚基4抗体

hz-9124R COPS7A  信号转导蛋白亚基7A抗体

hz-9125R COPS2/TRIP15  甲状腺受体相互作用蛋白15抗体

hz-9126R GPS1/CSN1  G蛋白通路抑制蛋白1抗体

hz-9127R Cullin 7  泛素连接酶CUL7蛋白抗体

hz-9128R CDCA7  细胞分裂周期相关蛋白

hz-9129R ASB12  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族12抗体

hz-9130R ASB4  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族4抗体

hz-9131R ASB9  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族9抗体

hz-9132R ASB8  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族8抗体

hz-9133R phospho-GPS1/CSN1(Ser474)  磷酸化G蛋白通路抑制蛋白1抗体

hz-9134R ASB7  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体

hz-9135R ASB17  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族17抗体

hz-9136R ASB5  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族5抗体

hz-9137R ZSWIM2  E3泛素蛋白连接酶ZSWIM2抗体

hz-9138R ZSWIM3  ZSWIM3蛋白抗体

hz-9139R ZNRF1  锌指/环指蛋白1抗体

hz-9140R ZNRF2  锌指/环指蛋白2抗体

hz-9141R ZNRF3  锌指蛋白3/环指蛋白3抗体

hz-9142R ZNRF4  锌指/环指蛋白4抗体

hz-9143R ZNF230/RNF141  锌指蛋白230抗体

hz-9144R UBR2  泛素蛋白连接酶E3α2抗体