周期素依赖性激酶样5抗体

英文名称    CDKL5    

中文名称    周期素依赖性激酶样5抗体    

别    名    Cdkl5; CDKL5_HUMAN; Cyclin dependent kinase 5 transcript; Cyclin-dependent kinase-like 5; EIEE2; ISSX; Serine/threonine kinase 9; Serine/threonine-protein kinase 9; Stk9.    

说 明 书    0.2ml      

研究领域    细胞生物  信号转导  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 周期素依赖性激酶样5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    115kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CDKL5 (401-500aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

周期素依赖性激酶样5抗体产品介绍    background:

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family. Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis, CDKL5 is thought to play a role in cell cycle regulation. Defects in CDKL5 are a cause of several disorders, such as X-linked infantile spasm syndrome and Rett syndrome.

Function:
Mediates phosphorylation of MECP2.    

周期素依赖性激酶样5抗体

hz-11185R CK19/CK17/CK14/CK10/CK42  细胞角蛋白19，17，14，42，10抗体

hz-11186R CK10/Cytokeratin 10  细胞角蛋白10抗体

hz-11187R CK42  细胞角蛋白42

hz-11188R CEBP gamma  转录调节因子C/EBPγ抗体

hz-11189R MRCK alpha/CDC42BPA  CDC42结合蛋白激酶α抗体（MRCKα）

hz-11190R C9  补体C9抗体

hz-11191R MRF/C11orf9  髓鞘基因调控因子抗体

hz-11192R NG2/CSPG4  黑色素瘤硫酸软骨素蛋白多糖4抗体

hz-11193R NSMase2  中性鞘磷脂2抗体

hz-11194R OLIG2  少突胶质细胞转录因子2抗体

hz-11195R ACL6B/BAF53b  肌动蛋白样蛋白6B抗体

hz-11196R R Cadherin  R Cadherin/CDH4

hz-11197R PRPH2  外周蛋白2抗体

hz-11198R ProSAPiP1   含脯氨酸突触相关蛋白相互作用蛋白1抗体

hz-11199R DBX1  脑发育同源蛋白1抗体

hz-11200R LHX2  调控胚胎干细胞分化蛋白Lhx2抗体

hz-4238R ARNT2   芳香烃受体核转录蛋白2抗体

hz-0045M AGT  血管紧张素原抗体

hz-4219R TBL1X  转导素β1X连锁蛋白抗体

hz-4110R GIT1  G蛋白偶联受体激酶相互作用蛋白1

hz-4220R TBLR1/TBL1XR1  转导素β1X连锁受体蛋白1抗体

hz-11201R Musashi 1/Msi1  神经干细胞RNA结合蛋白Musashi1抗体

hz-11202R NR2E1/Tailless  核受体蛋白NR2E1抗体

hz-11203R OCT6  八聚体结合转录因子6抗体

hz-11204R PAX6  转录因子Pax6抗体

hz-11206R PLAGL1/ZAC1  多型性腺瘤基因样蛋白1抗体

hz-11207R SOX22  核转录因子SOX22抗体

hz-11208R SOX4  核转录因子SOX4抗体

hz-11209R SUFU/Suppressor of Fused  抑制Hh信号通路蛋白SUFU抗体

hz-11210R DNAH9  轴丝动力蛋白重链9抗体

hz-5372R phospho-GIT1(Ser375)  磷酸化G蛋白偶联受体激酶相互作用蛋白1

hz-11211R KIF3A  驱动蛋白家族蛋白3抗体

hz-11212R KLC1/KNS2  驱动蛋白2抗体

hz-11213R LRRTM1  富含亮氨酸重复跨膜神经元蛋白1抗体