供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-6376R |
CAS号: |
英文名称 DDIT4L
中文名称 DNA损伤诱导转录样蛋白4抗体
别 名 DNA damage inducible transcript 4 like protein; HIF 1 responsive protein RTP801 like; Homolog of mouse SMHS1; Protein regulated in development and DNA damage response 2; REDD 2; REDD2; RTP801L; DDT4L_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 细胞周期蛋白 转录调节因子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 DNA损伤诱导转录样蛋白4抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDIT4L
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNA损伤诱导转录样蛋白4抗体产品介绍 background:
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. It is up regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Function:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Similarity:
Belongs to the DDIT4 family.
Database links:
UniProtKB/Swiss-Prot: Q96D03.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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