δ连环蛋白/δ连环素/δ链接素（δ-catenin）抗体

英文名称    Delta Catenin    

中文名称    δ连环蛋白/δ连环素/δ链接素（δ-catenin）抗体    

别    名    delta 1 Catenin; Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  干细胞  细胞骨架  细胞外基质      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 δ连环蛋白/δ连环素/δ链接素（δ-catenin）抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    106kDa    

细胞定位    细胞核 细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Delta Catenin    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

δ连环蛋白/δ连环素/δ链接素（δ-catenin）抗体产品介绍    background:

Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Function:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Subunit:
Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation. Detected at cell-cell contacts. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.

Subcellular Location:
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.

Tissue Specificity:
Expressed in vascular endothelium.

Post-translational modifications:
Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK7/PAK5. Dephosphorylated by PTPRJ.    

δ连环蛋白/δ连环素/δ链接素（δ-catenin）抗体

hz-0295G-hzy7 Goat Anti-rabbit IgG/Cy7  Cy7标记的羊抗兔IgG

hz-0295G-hzy5 Goat Anti-rabbit IgG/Cy5  Cy5标记的羊抗兔IgG

hz-0295G-PE-hzY5 Goat Anti-rabbit IgG/PE-CY5  PE-CY5标记的羊抗兔IgG

hz-0295G-PE Goat Anti-rabbit IgG/PE  PE标记的羊抗兔IgG

hz-0295G-hzy3 Goat Anti-rabbit IgG/Cy3  Cy3标记的羊抗兔IgG

hz-0295G-hzy5.5 Goat Anti-rabbit IgG/Cy5.5  Cy5.5标记的羊抗兔IgG

hz-0295G-PE-hzy3 Goat Anti-rabbit IgG/PE-Cy3  PE-Cy3标记的羊抗兔IgG

hz-0295G-APhz Goat Anti-rabbit IgG/APC  APC标记的羊抗兔IgG

hz-0295G-AF350 Goat Anti-rabbit IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗兔IgG

hz-0295G-AF488 Goat Anti-rabbit IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗兔IgG

hz-0295G-PE-hzy5.5 Goat Anti-rabbit IgG/PE-Cy5.5  PE-Cy5.5标记的羊抗兔IgG

hz-0295G-AF555 Goat Anti-rabbit IgG/Alexa Fluor 555  Alexa Fluor 555标记的羊抗兔IgG

hz-0295G-AF647 Goat Anti-rabbit IgG/Alexa Fluor 647  Alexa Fluor 647标记的羊抗兔IgG

hz-0295G-PE-hzy7 Goat Anti-rabbit IgG/PE-Cy7  PE-Cy7标记的羊抗兔IgG

hz-0295G-Bio Goat Anti-rabbit IgG/Bio  生物素标记的羊抗兔IgG

hz-0295G-AP Goat Anti-rabbit IgG/AP  碱性磷酸酶（AP）标记的羊抗兔IgG

hz-0295G-Gold Goat Anti-rabbit IgG/Gold  胶体金标记的羊抗兔IgG

hz-0295G-FIThz Goat Anti-rabbit IgG/FITC  FITC标记的羊抗兔IgG

hz-0295G-RBIThz Goat Anti-rabbit IgG/RBITC  罗丹明标记的羊抗兔IgG

hz-0310G-RBIThz Goat Anti-Chicken IgG/RBITC  罗丹明标记的羊抗鸡IgG

hz-0310G-Gold Goat Anti-Chicken IgG/Gold  胶体金标记的羊抗鸡IgG

hz-0310G-FIThz Goat Anti-Chicken IgG/FITC  FITC标记的羊抗鸡IgG

hz-0310G-hzy3 Goat Anti-Chicken IgG/Cy3  Cy3标记的羊抗鸡IgG

hz-0310G-hzy5 Goat Anti-Chicken IgG/Cy5  Cy5标记的羊抗鸡IgG

hz-0310G-hzy5.5 Goat Anti-Chicken IgG/Cy5.5  Cy5.5标记的羊抗鸡IgG

hz-0310G-hzy7 Goat Anti-Chicken IgG/Cy7  Cy7标记的羊抗鸡IgG

hz-0310G-PE Goat Anti-Chicken IgG/PE  PE标记的羊抗鸡IgG

hz-0310G-PE-hzy3 Goat Anti-Chicken IgG/PE-Cy3  PE-Cy3标记的羊抗鸡IgG

hz-0310G-PE-hzY5 Goat Anti-Chicken IgG/PE-CY5  PE-CY5标记的羊抗鸡IgG

hz-0310G-APhz Goat Anti-Chicken IgG/APC  APC标记的羊抗鸡IgG

hz-0310G-AF350 Goat Anti-Chicken IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗鸡IgG

hz-0310G-AF488 Goat Anti-Chicken IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗鸡IgG

hz-0310G-AF555 Goat Anti-Chicken IgG/Alexa Fluor 555  Alexa Fluor 555标记的羊抗鸡IgG