环氧化物水解酶1抗体

英文名称    Epoxide hydrolase 1    

中文名称    环氧化物水解酶1抗体    

别    名    EPHX 1; EPHX; EPHX1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal (xenobiotic); Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal (xenobiotic); HYEP_HUMAN; HYL1; MEH; Microsomal epoxide hydrolase.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 环氧化物水解酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    63kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Epoxide hydrolase 1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

环氧化物水解酶1抗体产品介绍    background:

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]

Function:
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.

Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Found in liver.

DISEASE:
Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls.
Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.

Similarity:
Belongs to the peptidase S33 family.

Gene ID:
2052

Database links:

Entrez Gene: 2052 Human

Entrez Gene: 535293 Cow

Entrez Gene: 13849 Mouse

Entrez Gene: 397639 Pig

Entrez Gene: 25315 Rat

Omim: 132810 Human

SwissProt: P07099 Human

SwissProt: Q9D379 Mouse

SwissProt: P79381 Pig

SwissProt: P07687 Rat

Unigene: 89649 Human

Unigene: 9075 Mouse

Unigene: 3603 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

环氧化物水解酶1抗体

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