供货周期: | 现货 |
品牌: | R&D |
规格: | g/mg |
货号: | hz-6642R |
CAS号: |
英文名称 FREAC3
中文名称 叉头相关转录因子3/FOXC1抗体
别 名 ARA; FKH L7; FKHL 7; FKHL7; Forkhead (Drosophila) like 7; Forkhead; forkhead box C1; Forkhead box protein C1; Forkhead drosophila homolog like 7; Forkhead like 7; Forkhead related activator 3; Forkhead related protein FKHL7; Forkhead related transcription factor 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FOX C1; FOXC 1; FOXC1; FOXC1_HUMAN; FREAC 3; FREAC-3; FREAC3; homolog-like 7; IGDA; IHG 1; IHG1; IRID 1; IRID1; Iridogoniodysgenesis type 1; Myeloid factor delta.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 发育生物学 转录调节因子 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 叉头相关转录因子3/FOXC1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FOXC1/FREAC3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
叉头相关转录因子3/FOXC1抗体产品介绍 background:
Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.
Involvement in disease; Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3); also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.
Function:
Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.
Subunit:
Monomer.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in all tissues and cell lines examined.
DISEASE:
Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA) [MIM:601631]. IGDA is an autosomal dominant phenotype characterized by iris hypoplasia, goniodysgenesis, and juvenile glaucoma.
[DISEASE] Defects in FOXC1 are a cause of Peters anomaly (PAN) [MIM:604229]. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea.
Similarity:
Contains 1 fork-head DNA-binding domain.
叉头相关转录因子3/FOXC1抗体
hz-4714R Salmonella 沙门氏菌抗体(多型)
hz-5846R ADAM11 去整合素样金属蛋白酶11抗体
hz-4715R Histone H3 (Tri Methyl K4) 三甲基化组蛋白H3抗体
hz-4718R MAGEA11 黑色素瘤相关抗原11抗体
hz-1385R ADAMTS12 整合素样金属蛋白酶与凝血酶1型-12抗体
hz-1930R ADH/AVP 抗利尿激素/血管升压素抗体(和肽素)
hz-4720R GDF9 生长分化因子9抗体
hz-4195R ADAM8 去整合素样金属蛋白酶8抗体
hz-4724R NT-3 神经营养因子3抗体
hz-4204R ADAM9 去整合素样金属蛋白酶9抗体
hz-5028R ABHD5 自水解酶结构域5蛋白抗体
hz-4727R MRC1/CD206 巨噬细胞甘露糖受体抗体
hz-4729R Bone Sialoprotein/BSP 骨涎蛋白
hz-4730R NOX4/NADPH oxidase 4 NADPH氧化酶4抗体
hz-4731R ABP1 植物生长激素ABP1抗体
hz-4734R Podoplanin Protein/gp36 平足蛋白抗体(淋巴管内皮细胞蛋白)
hz-4735R Cathelicidin 抗菌肽CAMP抗体
hz-4736R CD168/RHAMM 透明质酸介导细胞游走受体抗体
hz-4743R polyprotein[Classical swine fever virus, CSFV] 抗猪繁殖与呼吸综合征/猪蓝耳病病毒抗体
hz-4745R CSFV/Classical swine fever virus 猪瘟病毒抗体
hz-4746R CSFV/Classical swine fever virus 猪瘟病毒抗体
hz-4749R Integrin beta 6 整合素β6抗体(Integrin β6)
hz-4750R IFITM1/CD225 干扰素诱导跨膜蛋白1抗体
hz-4752R CSFV/Classical swine fever virus 猪瘟病毒抗体
hz-4753R NAPSIN A/ASP4 天冬氨酸蛋白酶ASP4抗体
hz-4755R CD19 CD19抗体
hz-4757R Nucleophosmin 核仁磷酸蛋白抗体
hz-4762R CK15 细胞角蛋白15抗体
hz-4763R CA153/hzA/Mucin-1 subunit alpha 乳腺癌相关抗原抗体
hz-4769R GRM2/GLUR2 促代谢型谷氨酸受体2抗体
hz-4770R CD133 造血干细胞抗原CD133抗体
hz-4772R Mucin 4/Muc4 粘蛋白-4抗体
相关产品
关注
拨打电话
留言咨询