F-box蛋白相关蛋白33抗体

英文名称    FBXO33    

中文名称    F-box蛋白相关蛋白33抗体    

别    名    F box only protein 33; Fbx 33; Fbx-33; Fbx33; FBX33_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）F-box蛋白相关蛋白33抗体 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    63kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FBXO33    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

F-box蛋白相关蛋白33抗体产品介绍    background:

Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin and F-box proteins act as protein-ubiquitin ligases and mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins.

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1 (By similarity).

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO33) formed of CUL1, SKP1, RBX1 and FBXO33. Interacts via its N-terminus with YBX1 CSD domain. Directly interacts with SKP1 and CUL1 (By similarity).

Similarity:
Contains 1 F-box domain.

Database links:
UniProtKB/Swiss-Prot: Q7Z6M2.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

F-box蛋白相关蛋白33抗体

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hz-9954R C12ORF63  12号染色体开放阅读框63抗体

hz-9955R C12ORF68  12号染色体开放阅读框68抗体

hz-9956R CRCT1  富含半胱氨酸C端蛋白1抗体

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hz-9971R CREPT  肿瘤高表达细胞周期相关蛋白抗体

hz-9972R LCA5L  致盲基因LCA5样蛋白抗体

hz-9973R LCA5  致盲基因LCA5蛋白抗体

hz-9974R C21ORF56  21号染色体开放阅读框56抗体

hz-9975R C21ORF62  21号染色体开放阅读框62抗体

hz-9976R C21orf128  21号染色体开放阅读框128抗体

hz-9977R C21orf2  21号染色体开放阅读框2抗体

hz-9978R C21orf58  21号染色体开放阅读框58抗体

hz-9979R C21orf70  21号染色体开放阅读框70抗体

hz-9980R C21orf55/DnaJC28  21号染色体开放阅读框55抗体

hz-9981R C21orf55/DnaJC28  21号染色体开放阅读框55抗体

hz-9982R C21orf87  21号染色体开放阅读框87抗体

hz-9983R EURL/C21orf91  21号染色体开放阅读框91抗体

hz-9984R C22orf25  22号染色体开放阅读框25抗体

hz-9985R HSPC117/C22orf28  22号染色体开放阅读框28抗体

hz-9986R C22orf36  22号染色体开放阅读框36抗体

hz-9987R C22orf9  22号染色体开放阅读框9抗体

hz-9988R C2CD2/C21orf25  21号染色体开放阅读框25抗体

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hz-9990R DGCR6L  无胸腺症关键蛋白6样抗体（迪格奥尔格综合征）

hz-9991R C4orf22  4号染色体开放阅读框22抗体

hz-9992R C4orf14  4号染色体开放阅读框14抗体

hz-9993R C4orf19  4号染色体开放阅读框19抗体