供货周期: | 现货 |
品牌: | CST |
规格: | g/mg |
货号: | hz-1692R |
CAS号: |
凋亡相关蛋白激酶3抗体产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
凋亡相关蛋白激酶3抗体产品介绍
DAPK3凋亡有关蛋白激酶3,属于丝/苏氨基酸蛋白激酶。 DAPK3 Mol. Weight: 52 kDa
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.
Also known as:
Death associated protein kinase 3; DAP kinase 3; DAP like kinase; Dapk 3; Dapk3; Death associated kinase 3; Death associated protein kinase 3; Dlk; EC 2.7.11.1; FLJ36473; ZIP; ZIP kinase; ZIPK
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