供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.2ml |
货号: | KL0059R |
CAS号: |
凋亡蛋白活性因子-1抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain,凋亡蛋白活性因子-1抗体 a caspase recruitment domain (CARD), and an ATPase domain(NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis.凋亡蛋白活性因子-1抗体 Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Also known as:
APAF 1; APAF1; APAF-1; Apoptotic peptidase activating factor 1; Apoptotic protease activating factor; CED 4; CED4; KIAA0413; APAF_HUMAN; Apoptotic protease-activating factor 1.
凋亡蛋白活性因子-1抗体Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Apaf-1.
●
Predicted Molecular Weight: 137kDa.
凋亡蛋白活性因子-1抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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