磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体

磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体Also known as:

Amyloid Precursor Protein (phospho Y757); Amyloid Precursor Protein (phospho Tyr757); p-Amyloid Precursor Protein (phospho Y757); phospho-Amyloid Precursor Protein (Tyr757); A4 amyloid protein; A4; A4_HUMAN; AAA; ABETA; ABPP; AD 1; AD1; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alzheimer disease 1; Alzheimer disease amyloid protein; Alzheimer disease; Alzheimer's disease amyloid protein; Amyloid beta (A4) precursor protein; Amyloid beta A4 protein; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform c; Amyloid beta A4 protein precursor isoform c; Amyloid beta A4 protein precursor isoform a; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform b;磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体 Amyloid beta A4 protein precursor isoform c; Amyloid beta A4 protein precursor isoform c; Amyloid beta protein; Amyloid beta-peptide; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid of aging and alzheimer disease; APP; APP I; APPI; Beta amyloid peptide; Beta-APP40; Beta-APP42; C31; Cerebral vascular amyloid peptide; CTFgamma; CVAP; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Human mRNA for amyloid A4 precursor of Alzheimer's disease; peptidase nexin II; PN 2; PN II; PN-II; PN2; PreA4; Protease nexin II; Protease nexin-II; S-APP-alpha; S-APP-beta; A4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human APP around the phosphorylation site of Tyr757.

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Predicted Molecular Weight: 3.4-9/83kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

bsp; 
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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