供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL2113R |
CAS号: |
AU5 tag标签抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. PreventsAU5 tag标签抗体 the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell AU5 tag标签抗体cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
AU5 tag标签抗体Also known as:
AU5 epitope tag; TDFYLK epitope tag; TDFYLK tag.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: fusion protein,tagged T7 tag.
●
Immunogen: KLH conjugated to AU5 tag.
AU5 tag标签抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 ICC=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl082Ra01层粘连蛋白γ1(LAMγ1)多克隆抗体Polyclonal Antibody to Laminin Gamma 1 (LAMC1)
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kl014Mu01骨成型蛋白4(BMP4)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 4 (BMP4)
kl014Ra01骨成型蛋白4(BMP4)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 4 (BMP4)
kl433Hu01蛋白激酶Cδ(PKCδ)多克隆抗体Polyclonal Antibody to Protein Kinase C Delta (PKCd)
kl433Mu01蛋白激酶Cδ(PKCδ)多克隆抗体Polyclonal Antibody to Protein Kinase C Delta (PKCd)
kl433Ra01蛋白激酶Cδ(PKCδ)多克隆抗体Polyclonal Antibody to Protein Kinase C Delta (PKCd)
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