磷酸化细胞凋亡信号调节激酶1抗体

报价:¥1
供货周期: 现货
品牌: 康朗生物
型号: 0.1ml/0.2ml
货号: KL3007R
上海康朗生物科技有限公司
银牌会员9年生产商
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产品详情

磷酸化细胞凋亡信号调节激酶1抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/磷酸化细胞凋亡信号调节激酶1抗体MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed磷酸化细胞凋亡信号调节激酶1抗体 in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.

磷酸化细胞凋亡信号调节激酶1抗体Also known as:

ASK1 (phospho S966); p-ASK1 (phospho S966); ASK1(Phospho-Ser966); Mitogen-activated protein kinase kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; Apoptosis signal-regulating kinase 1; ASK-1; MAP3K5; ASK1; MAPKKK5; MEKK5; M3K5_HUMAN.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, Chicken, Dog, Horse, .

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human ASK1 around the phosphorylation site of Ser966.

Predicted Molecular Weight: 152kDa.

磷酸化细胞凋亡信号调节激酶1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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磷酸化细胞凋亡信号调节激酶1抗体信息由上海康朗生物科技有限公司为您提供,如您想了解更多关于磷酸化细胞凋亡信号调节激酶1抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应磷酸化细胞凋亡信号调节激酶1抗体外,上海康朗生物科技有限公司还可为您提供AATK细胞凋亡关联酪氨酸激酶抗体、磷酸化Ack1抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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