有丝分裂激酶A/B/C抗体

?有丝分裂激酶A/B/C抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

?有丝分裂激酶A/B/C抗体Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. 

Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as?有丝分裂激酶A/B/C抗体 centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. 

The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.?有丝分裂激酶A/B/C抗体 This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Also known as:

AIK; ARK1; AURA; AURKA; Aurora 2; Aurora A; Aurora Family Kinase 1; aurora kinase A; Aurora Related Kinase 1; Aurora/IPL1 Like Kinase; Aurora/IPL1 Related Kinase 1; AURORA2; AYK1; BRAK; Breast Tumor Amplified Kinase; BTAK; hARK1; IAK; IPL1 Aurora Related Kinase 1; IPL1 Related Kinase; MGC34538.
AIK2; AIM1; ARK2; AurB; AURKB; Aurora 1; Aurora and Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora related kinase 2; Aurora-B; Aurora/IPL1 related kinase 2; IPL1; ?有丝分裂激酶A/B/C抗体Serine/theronine kinase 12; Serine/threonine protein kinase 12; STK1; STK12; STK5; AURKC; AIE2; AIK3; AurC; AURKC; Aurora C; Aurora/Ipl1 related kinase 3; IPL-1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; Serine threonine protein kinase 13; STK13; AURKA_HUMAN.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Aurora A/B/C.

●

Predicted Molecular Weight: 46kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 

kl635Hu01CUB带状疮疹透明区样域蛋白1(CUZD1)多克隆抗体Polyclonal Antibody to CUB And Zona Pellucida Like Domains Protein 1 (CUZD1)

kl644Hu01Neugrin蛋白(NGRN)多克隆抗体Polyclonal Antibody to Neugrin (NGRN)

kl648Hu01防御素β112(DEFβ112)多克隆抗体Polyclonal Antibody to Defensin Beta 112 (DEFb112)

kl656Hu01防御素β124(DEFβ124)多克隆抗体Polyclonal Antibody to Defensin Beta 124 (DEFb124)

kl660Hu01防御素β131(DEFβ131)多克隆抗体Polyclonal Antibody to Defensin Beta 131 (DEFb131)

kl746Hu01核糖核酸酶A10(RNASE10)多克隆抗体Polyclonal Antibody to Ribonuclease A10 (RNASE10)

kl820Hu01Enah/Vasp样蛋白(EVL)多克隆抗体Polyclonal Antibody to Enah/Vasp Like Protein (EVL)

kl943Hu01肽酶抑制因子16(PI16)多克隆抗体Polyclonal Antibody to Peptidase Inhibitor 16 (PI16)

kl971Hu01RNA结合基元蛋白24(RBM24)多克隆抗体Polyclonal Antibody to RNA Binding Motif Protein 24 (RBM24)

kl030Hu01序列相似家族5成员C(FAM5C)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 5, Member C (FAM5C)

kl142Mu01环氧化合物水解酶4(EPHX4)多克隆抗体Polyclonal Antibody to Epoxide Hydrolase 4 (EPHX4)

kl152Hu01含卷曲螺旋域蛋白3(CCDC3)多克隆抗体Polyclonal Antibody to Coiled Coil Domain Containing Protein 3 (CCDC3)

kl176Mu01血管生成素样蛋白7(ANGPTL7)多克隆抗体Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7)

kl493Hu01辅酶Q10同源物B(COQ10B)多克隆抗体Polyclonal Antibody to Coenzyme Q10 Homolog B (COQ10B)

kl574Hu01含MOCO硫化酶羧基端域蛋白1(MOSC1)多克隆抗体Polyclonal Antibody to MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1)

kl724Hu01纺锤体蛋白3(SPIN3)多克隆抗体Polyclonal Antibody to Spindlin 3 (SPIN3)

kl751Hu01谷氨酸脱羧酶样蛋白1(GADL1)多克隆抗体Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1)

kl758Mu01序列相似家族135成员B(FAM135B)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B)

Optimal working dilutions must be determined by the end user.