供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL5860R |
CAS号: |
?整合素样金属蛋白酶与凝血酶9型抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. ADAMTS9 is closest in homology to ADAMTS20,整合素样金属蛋白酶与凝血酶9型抗体 sharing 54% overall identity, and like ADAMTS20 ADAMTS9 gas a GON like domain at the carboxyterminal end. The GON domain at the carboxyterminal end is similar to the GON1 protein in C. elegans, mutations of which lead to defective gonadal development. ADAMTS9 is expressed in ovary and testis, but little is known about the role of ADAMTS9 in reproductive organs. ADAMTS9 is also expressed in the heart, placenta, lung, skeletal tissue, and pancreas, so the protein must have wider functions than just gonadal development. ADAMTS9, like ADAMTS20, has a total of 15 thrombospondin like domains. The first TS domain begins shortly after the catalytic and disintegrin domains. TS domains 2 to 6 follow a spacer domain, followed by linker domain 1, then TS domains 7 & 8, linker domain 2,整合素样金属蛋白酶与凝血酶9型抗体 and then TS domains 9 to 15. In other ADAMTS proteins the TS motifs are thought to bind to the ECM. The ADAMTS proteins contain at least one prohormone convertase cleavage site, although it appears that one site is used preferentially, and cleavage of the propeptide domain at this site generates active enzymes. For ADAMTS9, this site is the RRTKR sequence, and the mature ADAMTS9 has an aminoterminal sequence of FLSYPR. The catalytic site of ADAMTS9 is most like ADAMTS1, 14 and 15, with an HExxHVFNMxH sequence, perhaps giving these enzymes some shared specificity.
整合素样金属蛋白酶与凝血酶9型抗体Also known as:
A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A disintegrin and metalloproteinase with thrombospondin motifs 9; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 9; A disintegrin like and metalloprotease with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM TS 9; ADAM TS9; ADAMTS 9; ADAMTS9; ADAMTS-9; ATS9_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human ADAMTS9.
●
Predicted Molecular Weight: 181kDa.
整合素样金属蛋白酶与凝血酶9型抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl672Hu01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl672Mu01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl672Ra01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl673Ca01多巴胺受体D2(DRD2)多克隆抗体Polyclonal Antibody to Dokline Receptor D2 (DRD2)
kl673Hu01多巴胺受体D2(DRD2)多克隆抗体Polyclonal Antibody to Dokline Receptor D2 (DRD2)
kl675Hu01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl675Mu01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl675Ra01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl677Hu01凝血因子Ⅻ(F12)多克隆抗体Polyclonal Antibody to Coagulation Factor XII (F12)
kl677Mu01凝血因子Ⅻ(F12)多克隆抗体Polyclonal Antibody to Coagulation Factor XII (F12)
kl680Hu01棕榈酰化膜蛋白2(MPP2)多克隆抗体Polyclonal Antibody to Membrane Protein, klmitoylated 2 (MPP2)
kl680Ra01棕榈酰化膜蛋白2(MPP2)多克隆抗体Polyclonal Antibody to Membrane Protein, klmitoylated 2 (MPP2)
kl681Hu01乙醇脱氢酶1(ADH1)多克隆抗体Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1)
kl681Mu01乙醇脱氢酶1(ADH1)多克隆抗体Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1)
kl681Ra01乙醇脱氢酶1(ADH1)多克隆抗体Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1)
kl683Hu01Toll样受体6(TLR6)多克隆抗体Polyclonal Antibody to Toll Like Receptor 6 (TLR6)
kl685Hu01CD14分子(CD14)多克隆抗体Polyclonal Antibody to Cluster Of Differentiation 14 (CD14)
kl685Ra01CD14分子(CD14)多克隆抗体Polyclonal Antibody to Cluster Of Differentiation 14 (CD14)
kl687Hu01钙结合蛋白(CR)多克隆抗体Polyclonal Antibody to Calretinin (CR)
kl688Hu01TGFβ诱导早期应答基因1(TIEG1)多克隆抗体Polyclonal Antibody to TGF Beta Inducible Early Response Gene 1 (TIEG1)
kl690Hu01激肽释放酶8(KLK8)多克隆抗体Polyclonal Antibody to Kallikrein 8 (KLK8)
kl691Hu01激肽释放酶6(KLK6)多克隆抗体Polyclonal Antibody to Kallikrein 6 (KLK6)
相关产品
关注
拨打电话
留言咨询