β淀粉样蛋白前体结合蛋白B-1抗体

?β淀粉样蛋白前体结合蛋白B-1抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a gene that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. β淀粉样蛋白前体结合蛋白B-1抗体The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena.

β淀粉样蛋白前体结合蛋白B-1抗体Also known as:

AB1IP; Amyloid beta A4 precursor protein binding family B member 1 interacting protein; Amyloid beta precursor protein binding family B member 1; APBB1 interacting protein 1; OTTHUMP00000019344; PREL 1; PREL1; Proline rich EVH1 ligand 1; Proline rich protein 73; Rap1 GTP interacting adapter molecule; RAP1 interacting adaptor molecule; RARP 1;β淀粉样蛋白前体结合蛋白B-1抗体RARP1; Retinoic acid responsive proline rich protein 1; AB1IP_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human RIAM/APBB1 interacting protein 1.

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Predicted Molecular Weight: 73kDa.

β淀粉样蛋白前体结合蛋白B-1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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