供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL7738R |
CAS号: |
?胞环蛋白肌动蛋白结合蛋白抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
?Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system.胞环蛋白肌动蛋白结合蛋白抗体 It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis. Before the cell exits into G1, Anillin associates with E-cadherin and is ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C). APC/C recognizes the D-box domain at the N-terminal region of Anillin. Anillin is commonly overexpressed in tumors and may serve as a potential biomarker.Anillin is required for cytokinesis. 胞环蛋白肌动蛋白结合蛋白抗体It is essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.
Also known as:
Actin binding protein scraps homolog Drosophila; Actin binding protein anillin; Anillin actin binding protein; ANLN; DKFZp779A055; Scra; Scraps; Scraps homolog.
胞环蛋白肌动蛋白结合蛋白抗体Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Anillin.
●
Predicted Molecular Weight: 124kDa.
胞环蛋白肌动蛋白结合蛋白抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl024Hu01内分泌腺来源血管内皮生长因子(EG-VEGF)多克隆抗体Polyclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF)
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kl025Gu01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Hu01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Mu01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Ra01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
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