抑制蛋白结构域蛋白4抗体

参考价:¥1
供货周期: 现货
品牌: 康朗生物
规格: 0.1ml/0.2ml
货号: KL8078R
CAS号:
上海康朗生物科技有限公司
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产品详情

抑制蛋白结构域蛋白4抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ARRDC4 belongs to the arrestin family. The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, 抑制蛋白结构域蛋白4抗体or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own.抑制蛋白结构域蛋白4抗体 Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.

抑制蛋白结构域蛋白4抗体Also known as:

ARRDC 4; Arrestin domain containing protein 4; ARRD4_HUMAN.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Sheep, .

Immunogen: KLH conjugated synthetic peptide derived from human ARRDC4.

抑制蛋白结构域蛋白4抗体Predicted Molecular Weight: 45 kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl547Mu01血管细胞粘附分子1(VCAM1)多克隆抗体Polyclonal Antibody to Vascular Cell Adhesion Molecule 1 (VCAM1)

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kl548Hu01细胞间粘附分子1(ICAM1)多克隆抗体Polyclonal Antibody to Intercellular Adhesion Molecule 1 (ICAM1)

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抑制蛋白结构域蛋白4抗体信息由上海康朗生物科技有限公司为您提供,如您想了解更多关于抑制蛋白结构域蛋白4抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应抑制蛋白结构域蛋白4抗体外,上海康朗生物科技有限公司还可为您提供β-抑制蛋白2抗体/β休止蛋白2/β-arrestin抗体、β-抑制蛋白1/2抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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