小脑脊髓共济失调蛋白3抗体

?小脑脊髓共济失调蛋白3抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3) ; also known as Machado-Joseph disease (MJD). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders.?小脑脊髓共济失调蛋白3抗体 Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs,?小脑脊髓共济失调蛋白3抗体 peripheral neuropathy and dementia. The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region. Longer expansions result in earlier onset and more severe clinical manifestations of the disease.

Also known as:

?小脑脊髓共济失调蛋白3抗体ATX3L_HUMAN; ATXN3L; Machado-Joseph disease protein 1-like; MJDL; Putative ataxin-3-like protein.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, .

●

Immunogen: KLH conjugated synthetic peptide derived from human ATXN3L.

●

Predicted Molecular Weight: 41kDa.

?小脑脊髓共济失调蛋白3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl111Ge01苯丙氨酸(Phe)多克隆抗体Polyclonal Antibody to Phenylalanine (Phe)

kl780Ca01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Po01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Bo01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Cp01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Eq01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl720Ge01色氨酸(Trp)多克隆抗体Polyclonal Antibody to Tryptophan (Trp)

kl112Ge01酪氨酸(Tyr)多克隆抗体Polyclonal Antibody to Tyrosine (Tyr)

kl843Hu01促性腺激素释放激素(GnRH)多克隆抗体Polyclonal Antibody to Gonadotropin Releasing Hormone (GnRH)

kl843Mu01促性腺激素释放激素(GnRH)多克隆抗体Polyclonal Antibody to Gonadotropin Releasing Hormone (GnRH)

kl843Ra01促性腺激素释放激素(GnRH)多克隆抗体Polyclonal Antibody to Gonadotropin Releasing Hormone (GnRH)

kl843Fi01促性腺激素释放激素(GnRH)多克隆抗体Polyclonal Antibody to Gonadotropin Releasing Hormone (GnRH)

kl193Rb51溶菌酶(LZM)多克隆抗体Polyclonal Antibody to Lysozyme (LZM)

kl193Bo01溶菌酶(LZM)多克隆抗体Polyclonal Antibody to Lysozyme (LZM)

kl193Ga01溶菌酶(LZM)多克隆抗体Polyclonal Antibody to Lysozyme (LZM)

kl650Hu01主要碱性蛋白(MBP)多克隆抗体Polyclonal Antibody to Major Basic Protein (MBP)

kl650Mu01主要碱性蛋白(MBP)多克隆抗体Polyclonal Antibody to Major Basic Protein (MBP)

kl650Ra01主要碱性蛋白(MBP)多克隆抗体Polyclonal Antibody to Major Basic Protein (MBP)

kl650Po01主要碱性蛋白(MBP)多克隆抗体Polyclonal Antibody to Major Basic Protein (MBP)

kl908Ge01褪黑素(MT)多克隆抗体Polyclonal Antibody to Melatonin (MT)

kl575Hu01胃动素(MTL)多克隆抗体Polyclonal Antibody to Motilin (MTL)