磷酸化蛋白激酶AKT1抗体

?磷酸化蛋白激酶AKT1抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain.磷酸化蛋白激酶AKT1抗体 AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.

磷酸化蛋白激酶AKT1抗体Also known as:

AKT1 (phospho Y474); AKT1(phospho-Tyr474); AKT3 (phospho Y473); p-AKT3 (phospho Y473); phospho-AKT1(Tyr474); phospho-AKT2 (Tyr475); AKT1(phospho Tyr474); AKT2 (phospho Tyr475); AKT3(phospho Tyr473); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; 磷酸化蛋白激酶AKT1抗体RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .

●

Immunogen: KLH conjugated synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr474.

●

Predicted Molecular Weight: 56kDa.

磷酸化蛋白激酶AKT1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

l847Hu01抵抗素(RETN)多克隆抗体Polyclonal Antibody to Resistin (RETN)

kl847Mu01抵抗素(RETN)多克隆抗体Polyclonal Antibody to Resistin (RETN)

kl847Ra01抵抗素(RETN)多克隆抗体Polyclonal Antibody to Resistin (RETN)

kl848Hu01糖原磷酸化酶M(PYGM)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Muscle (PYGM)

kl848Mu01糖原磷酸化酶M(PYGM)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Muscle (PYGM)

kl848Ra01糖原磷酸化酶M(PYGM)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Muscle (PYGM)

kl849Hu01糖原磷酸化酶L(PYGL)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)

kl849Mu01糖原磷酸化酶L(PYGL)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)

kl849Ra01糖原磷酸化酶L(PYGL)多克隆抗体Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)

kl850Hu01肿瘤坏死因子配体超家族成员4(TNFSF4)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4)

kl852Hu01蛋白酶激活受体2(kl2)多克隆抗体Polyclonal Antibody to Protease Activated Receptor 2 (kl2)

kl852Mu01蛋白酶激活受体2(kl2)多克隆抗体Polyclonal Antibody to Protease Activated Receptor 2 (kl2)

kl852Ra01蛋白酶激活受体2(kl2)多克隆抗体Polyclonal Antibody to Protease Activated Receptor 2 (kl2)

kl853Hu01胱天蛋白酶8(CASP8)多克隆抗体Polyclonal Antibody to Caskle 8 (CASP8)

kl853Mu01胱天蛋白酶8(CASP8)多克隆抗体Polyclonal Antibody to Caskle 8 (CASP8)

kl853Ra01胱天蛋白酶8(CASP8)多克隆抗体Polyclonal Antibody to Caskle 8 (CASP8)

kl855Ga01核因子κB受体激活因子配基(RANκL)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

kl855Hu01核因子κB受体激活因子配基(RANκL)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

kl855Mu01核因子κB受体激活因子配基(RANκL)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

kl855Ra01核因子κB受体激活因子配基(RANκL)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL