磷酸化乙酰辅酶A羧化酶抗体

磷酸化乙酰辅酶A羧化酶抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes.磷酸化乙酰辅酶A羧化酶抗体 ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

磷酸化乙酰辅酶A羧化酶抗体Also known as:

Acetyl Coenzyme A Carboxylase alpha (phospho S80); p-Acetyl Coenzyme A Carboxylase alpha (phospho S80); ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC; ACC-alpha; ACC1; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化乙酰辅酶A羧化酶抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser80.

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Predicted Molecular Weight: 265kDa.

Storage:

磷酸化乙酰辅酶A羧化酶抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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