磷酸化肾上腺素能受体β2/β2-AR 抗体

?磷酸化肾上腺素能受体β2/β2-AR 抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, 磷酸化肾上腺素能受体β2/β2-AR 抗体cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.

磷酸化肾上腺素能受体β2/β2-AR 抗体Also known as:

beta 2 Adrenergic Receptor (phospho S346); p-beta 2 Adrenergic Receptor (phospho S346); β2-adrenergic receptor; beta 2 Adrenergic Receptor; ADRB2; ADRB2R; ADRBR; ADRB2_HUMAN; Adrenergic beta 2 receptor surface; B2AR; BAR; beta 2 adrenoceptor; Beta 2 adrenoreceptor; BETA2AR; Catecholamine receptor;磷酸化肾上腺素能受体β2/β2-AR 抗体 beta2-adrenergic receptor.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Dog, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human beta 2 Adrenergic Receptor around the phosphorylation site of Ser346.

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Predicted Molecular Weight: 46kDa.

磷酸化肾上腺素能受体β2/β2-AR 抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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