肿瘤/睾丸抗原2.3抗体

?肿瘤/睾丸抗原2.3抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Unknown. Candidate gene encoding tumor antigens. Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens.肿瘤/睾丸抗原2.3抗体 Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, 肿瘤/睾丸抗原2.3抗体lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.

Also known as:

B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3.

Specificity:

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Rabbit Polyclonal IgG,肿瘤/睾丸抗原2.3抗体 affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human BAGE3.

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肿瘤/睾丸抗原2.3抗体Predicted Molecular Weight: 10kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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