大脑富含鸟苷酸激酶相关蛋白抗体

?大脑富含鸟苷酸激酶相关蛋白抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

BEGAIN is a 593 amino acid protein that localizes to cytoplasm and membrane. BEGAIN interacts with PSD-95 and SAPAP1 and forms a ternary complex and may sustain the structure of the postsynaptic density (PSD). 大脑富含鸟苷酸激酶相关蛋白抗体BEGAIN is a novel PSD component associated with the core complex of PSD-95 and SAPAP. Because BEGAIN and SAPAP interact with the same region of PSD-95, BEGAIN and SAPAP may compete for the binding to PSD-95 and cannot interact with PSD-95 simultaneously. The C-terminal region of BEGAIN is involved in the interaction with PSD-95 whereas the N-terminal region has a coiled-coil structure that may interact with other molecules. BEGAIN is specifically expressed in brain and enriched in the PSD fraction. BEGAIN is also expressed in neurons and enriched at synaptic junctions,大脑富含鸟苷酸激酶相关蛋白抗体 and is likely involved in the organization of synaptic junction components.

Also known as:

BEGAIN; BEGIN; Brain enriched guanylate kinase associated protein; Brain-enriched guanylate kinase-associated homolog (rat); KIAA1446; SAP90/PSD95 Associated Proteins; SAPAP; BEGIN_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,大脑富含鸟苷酸激酶相关蛋白抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human BEGAIN.

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大脑富含鸟苷酸激酶相关蛋白抗体Predicted Molecular Weight: 65kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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