供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11808R |
CAS号: |
螺旋一环一螺旋蛋白5抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes. Class A proteins include the ubiquitously expressed E-box binding factors E12/E47,螺旋一环一螺旋蛋白5抗体 ITF2 and HEB (BETA 1 or HTF4). Class B proteins such as Myo D, myogenin and Neuro D (BETA 2) are transiently expressed and exhibit a more limited tissue distribution. Class A proteins heterodimerize with class B proteins to activate transcription. Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators. For instance, the Id family of transcriptional repressors contains a HLH region required for dimerization but lacks a functional DNA-binding domain.螺旋一环一螺旋蛋白5抗体 The Id family can therefore form heterodimers with the myogenic family, but the resulting complexes are transcriptionally inactive. BETA 3 is a protein that is functionally similar to members of the Id family in that it can inhibit the binding of E47 homodimers as well as E47/Neuro D and E47/Myo D heterodimers to consensus DNA sequences . In contrast to members of the Id family, BETA 3 contains a putative DNA-binding domain.
螺旋一环一螺旋蛋白5抗体Also known as:
BETA 3; Basic helix loop helix protein 5; Beta3; BHE22_HUMAN; bHLHB5; bHLHe22; CAGL85; Class B basic helix-loop-helix protein 5; Class E basic helix-loop-helix protein 22; Class II bHLH protein BHLHB5; TNRC20; Trinucleotide repeat containing 20; Trinucleotide repeat-containing gene 20 protein.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human BHLHB5.
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螺旋一环一螺旋蛋白5抗体Predicted Molecular Weight: 37kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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