磷酸化红细胞阴离子交换蛋白1抗体

?磷酸化红细胞阴离子交换蛋白1抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer.磷酸化红细胞阴离子交换蛋白1抗体 The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal, membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune system.磷酸化红细胞阴离子交换蛋白1抗体 An isoform of band 3, which lacks the first 65 amino acids and does not bind ankryin, is expressed in kidney.

Also known as:

Band 3 (phospho Y21); p-Band 3 (phospho Y21); Solute carrier family 4 anion exchanger member 1; Solute carrier family 4 member 1; AE 1; AE1; Anion exchange protein 1; Anion exchanger 1; B3AT_HUMAN; Band 3; Band 3 anion transport protein; BND3; CD233; DI; Diego blood group; EMPB3;磷酸化红细胞阴离子交换蛋白1抗体 EPB3; Erythrocyte membrane protein band 3; Erythroid anion exchange protein; FR antibod; Froese blood group; RTA1A; SLC4A1; Solute carrier family 4 member 1; SW antibody; Swann blood group; Waldner blood group; WD antibody; WD1; WR antibody; Wright blood group.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Dog, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human Band3 around the phosphorylation site of Tyr21.

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磷酸化红细胞阴离子交换蛋白1抗体Predicted Molecular Weight: 102kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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