磷酸化Bcl-2抗体

?磷酸化Bcl-2抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.磷酸化Bcl-2抗体 Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD,磷酸化Bcl-2抗体 BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.

Also known as:

Bcl2 (phospho S87); Bcl2 (phospho Ser87); p-Bcl2 (phospho S87); p-Bcl2 (Ser87); Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik;磷酸化Bcl-2抗体 D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN; Apoptosis regulator Bcl-2.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthesised phosphopeptide derived from human Bcl2 around the phosphorylation site of Ser87.

●

磷酸化Bcl-2抗体Predicted Molecular Weight: 26kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl218Ra01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl124Hu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Mu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ra01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Gu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Rb51转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ca01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Bo01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Po01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Cp01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Eq01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ga01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl765Hu01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl765Mu01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl765Ra01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl312Hu01血管紧张素Ⅲ(AngⅢ)多克隆抗体Polyclonal Antibody to Angiotensin III (AngIII)

kl005Hu01血管紧张素Ⅱ(ANGⅡ)多克隆抗体Polyclonal Antibody to Angiotensin II (AngII)

kl851Ge01多巴胺(DA)多克隆抗体Polyclonal Antibody to Dokline (DA)