供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL12578R |
CAS号: |
?磷酸化Bcl-2抗体Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.磷酸化Bcl-2抗体 Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD,磷酸化Bcl-2抗体 BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL
Also known as:
Bcl2 (Phospho-Thr69); Bcl2 (Phospho-T69); Bcl2 (phospho T69); p-Bcl2 (phospho T69); Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik;磷酸化Bcl-2抗体 D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN; Apoptosis regulator Bcl-2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Bcl-2 around the phosphorylation site of Thr69.
●
磷酸化Bcl-2抗体Predicted Molecular Weight: 26kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
l455Ge01雌三醇(E3)多克隆抗体Polyclonal Antibody to Estriol (E3)
kl461Ge01雌二醇(E2)多克隆抗体Polyclonal Antibody to Estradiol (E2)
kl912Ge01乙酰胆碱(ACH)多克隆抗体Polyclonal Antibody to Acetylcholine (ACH)
kl927Ge01组胺(HA)多克隆抗体Polyclonal Antibody to Histamine (HA)
kl051Ge01视黄醇(Ret)多克隆抗体Polyclonal Antibody to Retinol (Ret)
kl463Hu01促甲状腺素(TSH)多克隆抗体Polyclonal Antibody to Thyroid Stimulating Hormone (TSH)
kl463Mu01促甲状腺素(TSH)多克隆抗体Polyclonal Antibody to Thyroid Stimulating Hormone (TSH)
kl463Ra01促甲状腺素(TSH)多克隆抗体Polyclonal Antibody to Thyroid Stimulating Hormone (TSH)
kl215Hu01中心体肌动蛋白β(CTRN2)多克隆抗体Polyclonal Antibody to Centractin Beta (CTRN2)
kl215Mu01中心体肌动蛋白β(CTRN2)多克隆抗体Polyclonal Antibody to Centractin Beta (CTRN2)
kl215Ra01中心体肌动蛋白β(CTRN2)多克隆抗体Polyclonal Antibody to Centractin Beta (CTRN2)
kl297Hu01核糖核酸酶A(RNASE1)多克隆抗体Polyclonal Antibody to Ribonuclease A (RNASE1)
kl762Hu01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)
kl762Mu01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)
kl762Ra01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)
kl178Hu01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)
kl178Mu01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)
kl178Ra01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)
kl545Hu01免疫球蛋白E(IgE)多克隆抗体Polyclonal Antibody to Immunoglobulin E (IgE)
kl545Mu01免疫球蛋白E(IgE)多克隆抗体Polyclonal Antibody to Immunoglobulin E (IgE)
相关产品
关注
拨打电话
留言咨询