核糖体合成蛋白BOP1抗体

核糖体合成蛋白BOP1抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis,核糖体合成蛋白BOP1抗体 as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, 核糖体合成蛋白BOP1抗体thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.

Also known as:

核糖体合成蛋白BOP1抗体AU020183; AW146150; Block of proliferation 1; Block of proliferation 1 protein; Bop1; Bop1 block of proliferation 1; BOP1_HUMAN; D18861; Erb1p; Kiaa0124; MGC109114; mKIAA0124; Ribosome biogenesis protein BOP1.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human BOP1.

●

Predicted Molecular Weight: 84kDa.

核糖体合成蛋白BOP1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl846Ra01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl869Hu01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl869Mu01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl869Ra01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl986Hu01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl986Mu01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl986Ra01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl833Hu01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl833Mu01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl833Ra01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl603Hu01载脂蛋白B100(APOB100)多克隆抗体Polyclonal Antibody to Apolipoprotein B100 (APOB100)

kl603Ra01载脂蛋白B100(APOB100)多克隆抗体Polyclonal Antibody to Apolipoprotein B100 (APOB100)

kl603Mu01载脂蛋白B100(APOB100)多克隆抗体Polyclonal Antibody to Apolipoprotein B100 (APOB100)

kl003Hu01载脂蛋白B(APOB)多克隆抗体Polyclonal Antibody to Apolipoprotein B (APOB)

kl003Mu01载脂蛋白B(APOB)多克隆抗体Polyclonal Antibody to Apolipoprotein B (APOB)

kl003Ra01载脂蛋白B(APOB)多克隆抗体Polyclonal Antibody to Apolipoprotein B (APOB)

kl704Hu01载脂蛋白E(APOE)多克隆抗体Polyclonal Antibody to Apolipoprotein E (APOE)

kl704Mu01载脂蛋白E(APOE)多克隆抗体Polyclonal Antibody to Apolipoprotein E (APOE)